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Top Ten: Weekend reads: Would you volunteer for a COVID-19 vaccine trial?

Also, a hot housing market, interesting retirement destinations and heartfelt advice from the Moneyist. Read More...

It’s encouraging that so many biotech and pharmaceutical companies are working on COVID-19 vaccines. Researchers will need a lot of volunteers to run human trials.

Maybe you should participate. Arlene Weintraub profiles the type of person vaccine developers want for trials, along with what to expect if you participate, the chance of getting a placebo and possible side effects.

Record-low mortgage rates

Jacob Passy describes what should be a borrower’s paradise, but is turning out to be a difficult market for home buyers.

A mural outside Andy’s Bar, one of dozens of murals painted on buildings in Denton, Texas.

Victoria DeCuir/ Courtesy Denton Public Library

Retirement destinations

Silvia Ascarelli helps a woman who wants to retire and move from Maine to Texas, with three possible destinations.

A potential coronavirus medication kept off the market

Gilead’s remdesivir medication is a well-known treatment for people suffering from COVID-19 infections, but Rex Nutting says another Gilead medication may be more effective, at lower cost, but that the company is refusing to test it.

Despite this year’s incredible rise, the price of gold relative to the S&P 500 Index is low, based on this 30-year chart.

FactSet

The case for gold …

Above is a chart showing the price of gold relative to the level of the S&P 500 Index over the past 30 years. Gold GC00, +0.89% is relatively cheap against the benchmark index, even after its remarkable rise this year. That is among several reasons Michael Cuggino, CEO of the Permanent Portfolio Family of Funds, believes gold may head to $4,000 an ounce.

Related:Gold is hitting new highs — these are the stocks to consider buying now

… and the case against gold

But Mark Hulbert says gold’s “fundamental value,” adjusted for inflation, is so high right now that it would be foolish for investors to buy.

This man is 52 — should he retire?

Alessandra Malito helps a man in an interesting set of (mostly good) circumstances decide whether early retirement is right for him.

MarketWatch photo illustration/iStockphoto
A timely retirement question

What if your parents aren’t prepared for retirement, and time is getting short?

Bringing baggage into a marriage

Quentin Fottrell — MarketWatch’s Moneyist — helps a man whose fiancée is divorced, and worried she may be on the hook for her ex-husband’s $100,000 delinquent tax bill.

A rosy prediction

Michael Brush expects the stock market to be riding high a year from now.

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